HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanogen Bromide → N-Ethyl-N-{[(4S)-2-imino-1,3-oxazolidin-4-yl]methyl}aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanogen Bromide | HCID 10476 | — |
| Reactant | HCID 57667077 | HCID 57667077 | — |
| Product | N-Ethyl-N-{[(4S)-2-imino-1,3-oxazolidin-4-yl]methyl}aniline | HCID 25016538 | — |
Reaction Steps
In analogy to example 1.d (S)-2-amino-3-(ethyl-phenyl-amino)-propan-1-ol was reacted with cyanogen bromide to give (S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine. Off-white solid. MS (ISP): 220.4 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902238B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-be0a087a7bf845bc9fb453aeed0e3740 |
| Source note | uspto-grants-2011_03 |