Trifluoroacetic acid → HCID 58976163, compound

Participants

Reaction Steps

A mixture of 4-[4-(5-amino-1-pyridin-2-yl-1H-[1,2,4]triazol-3-ylamino)-benzoyl]-piperazine-1-carboxylic acid tert-butyl ester (22.1 mg) and trifluoroacetic acid (0.50 mL) was stirred at room temperature for 1 h. The reaction mixture was concentrated to give the title compound (13.6 mg) as a white solid. MS (ES+): m/z=365.1; 1H NMR (CD3SOCD3, 500 MHz): δ 3.09-3.23 (m, 4H), 3.63-3.76 (m, 4H), 7.20-7.25 (m, 1H), 7.41 (d, 2H), 7.64-7.74 (m, 4H), 7.95-8.02 (m, 1H), 8.39-8.44 (m, 1H), 8.66-8.95 (m, 2H), 9.44-9.48 (m, 1H).

Provenance & Evidence