Methanol → Methyl (benzylthio)acetate

HRID 601086Notes

Reaction equation

HRID 601086 reaction equation
[CH2:1]([S:8][CH2:9][C:10]([OH:12])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:13]O>>[CH2:1]([S:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 887MethanolHCID 668972-((Phenylmethyl)thio)acetic acid

Product 1

HCID 562502Methyl (benzylthio)acetate

Procedure

S-benzylthioglycolic acid (12.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 20 minutes. The solvent was then removed under vacuum. Methyl S-benzylthioglycolate obtained was used in the next step without further purification.

Workup

  1. customsparged with hydrogen chloride gas at room temperature for 20 minutes
  2. customThe solvent was then removed under vacuum

Sources & evidence

ORD record
ord-687a83844f2349f38643e143c09e5da5
Source dataset
uspto-grants-2011_03
Patent number
US07902259B2

Reaction notes

Loading…