P-Cresol → HCID 54398422, compound

Participants

Reaction Conditions

Reaction Steps

This example illustrates a reaction system comprising two reactors and providing for a two tiered temperature profile for forming styrenated p-cresol. 50 Kg (110.2 lb, 462.2 moles) p-cresol was pumped from a preheated drum into a 50 gallon glass lined steel jacketed reactor equipped with an agitator, thermowell, and a pump around loop for sampling and acid injection. The p-cresol was heated to about 60° C. followed by the addition of 1.6 to 8.3 g (5.53e-05 to 1.07e-02 moles) of trifluoromethane sulfonic acid via a syringe in an injection port of the pump around loop. 93.9 Kg (2071b, 901.6 moles) styrene was fed through a mass flow meter at a constant rate over a 3 to 4 hour reaction time where the reactor temperature was maintained at 70° C. The molar ratio of styrene to p-cresol fed was maintained at 1.95. After the completion of the styrene feed, the reactor contents were pumped to a second 50 gallon glass lined steel jacketed reactor and heated to 90° C. Approximately 1.5 lb (0.7 Kg) of acid-leached bentonite clay (Filtrol 20×) was added through a man hole to the second reactor and agitated for 15 minutes. The product was then pumped to a bag filter and into product drums. The typical sample result from this production, based on total GC area, are provided below in TABLE 10.

Provenance & Evidence