HCID 29781548, compound → HCID 86592110, compound

HRID 601117Notes

Reaction equation

HRID 601117 reaction equation
[CH2:1]([CH:3]([NH:6][C:7]1[N:17]=[CH:16][CH:15]=[CH:14][C:8]=1[C:9]([O:11][CH2:12]C)=[O:10])[CH2:4][CH3:5])[CH3:2].C(C(CC)CNC1N=CC=CC=1C(OCC)=[O:26])C>>[CH2:1]([CH:3]([N:6]1[C:7]2[N:17]=[CH:16][CH:15]=[CH:14][C:8]=2[C:9](=[O:10])[O:11][C:12]1=[O:26])[CH2:4][CH3:5])[CH3:2]

Participants

3

Reactant 2

HCID 29781548HCID 29781548, compoundHCID 67064133Ethyl 2-[(2-ethylbutyl)amino]nicotinate

Product 1

HCID 86592110HCID 86592110, compound

Procedure

The title compound was prepared according to the procedure of Example 3B substituting the product of Example 64A for the product of Example 3A (0.120 g, 57%). MS (ESI+) m/z 223.1 (M+H)+; 1H NMR (300 MHz, CDCl3) δ 0.87 (t, J=7.54 Hz, 6H), 1.88 (m, 2H), 2.21 (s, 2H), 5.43 (s, 1H), 7.24 (dd, J=6.99, 4.04 Hz, 1H), 8.42 (dd, J=7.72, 1.84 Hz, 1H), 8.68 (dd, J=4.78, 1.84 Hz, 1H).

Sources & evidence

ORD record
ord-8997bee6595641d1b176bc9b142f7029
Source dataset
uspto-grants-2011_03
Patent number
US07902203B2

Reaction notes

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