Ethyl 2-[(3-ethoxy-3-oxopropanoyl)(propoxy)amino]benzoate → Ethyl 4-hydroxy-2-oxo-1-propoxy-1,2-dihydroquinoline-3-carboxylate

HRID 601165Notes

Reaction equation

HRID 601165 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[CH2:5][C:6]([N:8]([O:20][CH2:21][CH2:22][CH3:23])[C:9]1[CH:19]=[CH:18][CH:17]=[CH:16][C:10]=1[C:11]([O:13]CC)=O)=[O:7])[CH3:2].C(ON(C(=O)CC(OCC)=O)C1N=CC=CC=1C(OCC)=O)C1C=CC=CC=1>>[OH:13][C:11]1[C:10]2[C:9](=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:8]([O:20][CH2:21][CH2:22][CH3:23])[C:6](=[O:7])[C:5]=1[C:4]([O:3][CH2:1][CH3:2])=[O:24]

Participants

3

Reactant 2

HCID 85970220Ethyl 2-[(3-ethoxy-3-oxopropanoyl)(propoxy)amino]benzoateHCID 86592121Ethyl 2-[(benzyloxy)(3-ethoxy-3-oxopropanoyl)amino]nicotinate

Product 1

HCID 67063576Ethyl 4-hydroxy-2-oxo-1-propoxy-1,2-dihydroquinoline-3-carboxylate

Procedure

The title compound is prepared according to the procedure of Example 157C substituting the product of Example 172C for the product of Example 157B.

Sources & evidence

ORD record
ord-2788c5615fbb4df7a953a5239419b35a
Source dataset
uspto-grants-2011_03
Patent number
US07902203B2

Reaction notes

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