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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 601169Generated: October 25, 2026

2-Amino-5-bromobenzenesulfonamide → N-[2-(aminosulfonyl)-5-chlorothien-3-yl]-1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide

https://huagongshe.com/reaction/601169

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-bromobenzenesulfonamideHCID 820700—
Reactant3-Amino-5-chlorothiophene-2-sulfonamideHCID 10955934—
ReactantEthyl 1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylateHCID 54711837—
ProductN-[2-(aminosulfonyl)-5-chlorothien-3-yl]-1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamideHCID 67063731—

Reaction Steps

The title compound is prepared according to the procedure of Example 84C substituting the product of Example 174A for the product of Example 84A and substituting the product of Example 99A for the product of example Example 84B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902203B2
Source datasetuspto-grants-2011_03
ORD IDord-28bde75c0e594c23bc7208f753ae7cbe
Source noteuspto-grants-2011_03