HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 601220Generated: October 29, 2026
Cyclopropyl methyl ketone → HCID 136373982, compound
https://huagongshe.com/reaction/601220
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyclopropyl methyl ketone | HCID 13004 | — |
| Reactant | 4-amino-6-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-7-hydroxythieno[3,2-b]pyridin-5(4H)-one | HCID 136373627 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 136373982 | HCID 136373982 | — |
Reaction Steps
The product of Example 268D (0.065 g, 0.18 mmol) was reacted with 1-cyclopropylethanone (0.54 g, 6.4 mmol) in N,N-dimethylacetamide (2 mL) in a sealed tube at 135° C. for 120 minutes in a microwave reactor. The reaction was cooled to 25° C. and concentrated under vacuum. The resulting residue was triturated with ethyl acetate/hexane (2:1) and filtered to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07902203B2 |
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| Source dataset | uspto-grants-2011_03 |
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| ORD ID | ord-b9f9a39100a74ec1a2ec7800d43b2030 |
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| Source note | uspto-grants-2011_03 |
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