HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 601236Generated: October 29, 2026
3-Methyl-2-butenal → HCID 136376457, compound
https://huagongshe.com/reaction/601236
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Methyl-2-butenal | HCID 61020 | — |
| Reactant | 4-amino-6-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-7-hydroxythieno[3,2-b]pyridin-5(4H)-one | HCID 136373627 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 136376457 | HCID 136376457 | 80.4% |
Reaction Steps
The product of Example 268D (0.10 g, 0.27 mmol) was reacted with 3-methylbut-2-enal (0.5 g, 5.9 mmol) in N,N-dimethylacetamide (3 mL) in a sealed tube at 130° C. for 40 minutes in a microwave reactor. The reaction was cooled to 25° C. and concentrated under vacuum. The resulting residue was triturated with diethyl ether and filtered to give the title compound (0.093 g, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07902203B2 |
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| Source dataset | uspto-grants-2011_03 |
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| ORD ID | ord-f49f7f50d5c943a886b539bbc555f098 |
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| Source note | uspto-grants-2011_03 |
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