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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 601676Generated: October 29, 2026

HCID 23158122, compound → HCID 58328316, compound

https://huagongshe.com/reaction/601676

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23158122HCID 23158122—
ReactantHCID 178418361HCID 178418361—
CatalystHCID 178418390HCID 178418390—
SolventEthanolHCID 702—
ProductHCID 58328316HCID 5832831669.6%

Reaction Steps

30 mg of palladium carbon was added to 10 ml of ethanol solution with 10 mg of 4-(2-isopropyl-1-oxo-isoquinoline-6-yl)-1-(2-fluoropyridine-3-yl)-5-methyl-1H-[1,2,3]triazole, and hydrogen was added under 4 atm of hydrogen pressure. 8 hours later, the reaction solution was filtrated and after distilling out the solvents of the filtrate under reduced pressure, the residues were separated and purified by thin-layer chromatography (chloroform/methanol=10/1) to obtain 7 mg of the above compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902369B2
Source datasetuspto-grants-2011_03
ORD IDord-e485e07a686d4f61928ef879adb34a7d
Source noteuspto-grants-2011_03