HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 59180081, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | Bicyclo[3.1.0]hexan-3-one | HCID 549318 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59180081 | HCID 59180081 | — |
Reaction Steps
Bicyclo[3.1.0]hexan-3-one (192 mg, 2.0 mmol) was reacted with POCl3, (0.33 mL, 3.6 mmol) and dry DMF (0.31 mL, 4.0 mmol) in dry CH2Cl2 (0.3 mL) according to General Procedure 1.1.A. The material was purified by passing through a pad of silica gel eluting with Et2O to afford the title compound. The material was used as is in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902252B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-4974b6cf61274c90b4a21cf112040461 |
| Source note | uspto-grants-2011_03 |