HuagongsheHuagongshe Chemistry Print Report · For research reference only
o-Fluorobenzaldehyde → 2-[3-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]methoxymethyl]piperidin-1-yl]benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | o-Fluorobenzaldehyde | HCID 67970 | — |
| Reactant | 3-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]methoxymethyl]piperidine | HCID 57572215 | — |
| Product | 2-[3-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]methoxymethyl]piperidin-1-yl]benzaldehyde | HCID 57572203 | 32.5% |
Reaction Steps
Using 3-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]methoxymethyl]piperidine (106 mg, 0.315 mmol) and 2-fluorobenzaldehyde (0.0329 mL, 0.315 mmol), the same procedure was followed as in Step 1c of Example 1 to give 45.2 mg (32%) of the desired compound as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902367B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-e5dd7d6d70524c96813243a2587e9421 |
| Source note | uspto-grants-2011_03 |