HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]methoxy]piperidine → Methyl 3-[3-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]methoxy]piperidin-1-yl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]methoxy]piperidine | HCID 57572149 | — |
| Reactant | 3-Methoxycarbonylphenylboric acid | HCID 67170287 | — |
| Product | Methyl 3-[3-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]methoxy]piperidin-1-yl]benzoate | HCID 58992606 | 72% |
Reaction Steps
Using 3-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]methoxy]piperidine (60.2 mg, 0.186 mmol) and 3-(methoxycarbonyl)phenylboric acid (66.9 mg, 0.372 mmol), the same procedure was followed as in Example 2 to give 61.0 mg (72%) of the desired compound as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902367B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-bebcab066b2e47f39b8610b154c97af9 |
| Source note | uspto-grants-2011_03 |