HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(piperidin-3-yl)-2-[2-(4-chlorophenyl)-4-methylthiazol-5-yl]acetamide → Methyl 3-[3-[2-[2-(4-chlorophenyl)-4-methylthiazol-5-yl]acetylamino]piperidin-1-yl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(piperidin-3-yl)-2-[2-(4-chlorophenyl)-4-methylthiazol-5-yl]acetamide | HCID 58992603 | — |
| Reactant | 3-Methoxycarbonylphenylboric acid | HCID 67170287 | — |
| Product | Methyl 3-[3-[2-[2-(4-chlorophenyl)-4-methylthiazol-5-yl]acetylamino]piperidin-1-yl]benzoate | HCID 58992668 | 59% |
Reaction Steps
Using N-(piperidin-3-yl)-2-[2-(4-chlorophenyl)-4-methylthiazol-5-yl]acetamide (200 mg, 0.572 mmol) and 3-(methoxycarbonyl)phenylboric acid (205 mg, 1.14 mmol), the same procedure was followed as in Example 2 to give 162 mg (59%) of the desired compound as a colorless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902367B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-6b092c620d3b4ca8baba6a2a90df1df1 |
| Source note | uspto-grants-2011_03 |