HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic acid, 2-fluoro-, methyl ester → Benzyl 1-[2-(methoxycarbonyl)phenyl]nipecotate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic acid, 2-fluoro-, methyl ester | HCID 67854 | — |
| Reactant | Benzyl piperidine-3-carboxylate | HCID 13419237 | — |
| Product | Benzyl 1-[2-(methoxycarbonyl)phenyl]nipecotate | HCID 58992661 | 17.3% |
Reaction Steps
Using benzyl nipecotate (5.90 g, 26.9 mmol) and methyl 2-fluorobenzoate (3.70 mL, 29.0 mmol), the same procedure was followed as in Step 1c of Example 1 to give 1.64 g (17%) of the desired compound as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902367B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-c845ae67d8494a35af623cc8496dbc01 |
| Source note | uspto-grants-2011_03 |