HCID 45786769, compound → HCID 58992684, compound

HRID 602177Notes

Reaction equation

HRID 602177 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[O:10][CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][NH:14][CH2:13]1.[CH3:18][O:19][C:20]([C:22]1[CH:23]=[C:24](OB(O)O)[CH:25]=[CH:26][CH:27]=1)=[O:21]>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[O:10][CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][N:14]([C:26]2[CH:27]=[C:22]([CH:23]=[CH:24][CH:25]=2)[C:20]([O:19][CH3:18])=[O:21])[CH2:13]1

Participants

3

Reactant 2

HCID 45786769HCID 45786769, compoundHCID 671702873-Methoxycarbonylphenylboric acid

Product 1

HCID 58992684HCID 58992684, compoundYield 20%

Procedure

Using 3-[(benzothiazol-2-yl)oxymethyl]piperidine (58.0 mg, 0.234 mmol) and 3-(methoxycarbonyl)phenylboric acid (84.2 mg, 0.468 mmol), the same procedure was followed as in Example 2 to give 17.6 mg (20%) of the desired compound as a colorless oil.

Sources & evidence

ORD record
ord-123c65d495124b1c9a609e87dc2816bb
Source dataset
uspto-grants-2011_03
Patent number
US07902367B2

Reaction notes

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