HCID 58992689, compound → HCID 58992658, compound

HRID 602189Notes

Reaction equation

HRID 602189 reaction equation
[F:1][C:2]1[CH:23]=[CH:22][C:5]([O:6][C:7]2[CH:21]=[CH:20][C:10]([CH2:11][O:12][CH2:13][CH:14]3[CH2:19][CH2:18][CH2:17][NH:16][CH2:15]3)=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.[CH3:24][O:25][C:26]([C:28]1[CH:29]=[C:30](OB(O)O)[CH:31]=[CH:32][CH:33]=1)=[O:27]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:6][C:7]2[CH:21]=[CH:20][C:10]([CH2:11][O:12][CH2:13][CH:14]3[CH2:19][CH2:18][CH2:17][N:16]([C:32]4[CH:33]=[C:28]([CH:29]=[CH:30][CH:31]=4)[C:26]([O:25][CH3:24])=[O:27])[CH2:15]3)=[CH:9][CH:8]=2)=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 58992689HCID 58992689, compoundHCID 671702873-Methoxycarbonylphenylboric acid

Product 1

HCID 58992658HCID 58992658, compoundYield 57.3%

Procedure

Using 3-[4-(4-fluorophenoxy)benzyloxymethyl]piperidine (35.7 mg, 0.113 mmol) and 3-(methoxycarbonyl)phenylboric acid (40.7 mg, 0.226 mmol), the same procedure was followed as in Example 2 to give 29.1 mg (57%) of the desired compound as a colorless oil.

Sources & evidence

ORD record
ord-83791c85a2ff4ff7aad9249293c231d5
Source dataset
uspto-grants-2011_03
Patent number
US07902367B2

Reaction notes

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