HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxycarbonylphenylboric acid → Methyl 3-[3-[2-[2-(4-chlorophenyl)-4-methylthiazol-5-yl]ethenyl]piperidin-1-yl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxycarbonylphenylboric acid | HCID 67170287 | — |
| Reactant | 3-[2-[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]ethenyl]piperidine | HCID 67267078 | — |
| Product | Methyl 3-[3-[2-[2-(4-chlorophenyl)-4-methylthiazol-5-yl]ethenyl]piperidin-1-yl]benzoate | HCID 67267835 | 36% |
Reaction Steps
Using 3-[2-[2-(4-chlorophenyl)-4-methylthiazol-5-yl]ethenyl]piperidine (153 mg, 0.480 mmol) and 3-(methoxycarbonyl)phenylboric acid (173 mg, 0.960 mmol), the same procedure was followed as in Example 2 to give 77.7 mg (36%) of the desired compound as a yellow powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902367B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-eb5f265c286747b59d152ed2e6dbc825 |
| Source note | uspto-grants-2011_03 |