HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(morpholin-2-yl methyl)-2-(4-chlorophenyl)-4-methylthiazole-5-carboxamide → Methyl 3-[2-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]carbonylaminomethyl]morpholin-4-yl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(morpholin-2-yl methyl)-2-(4-chlorophenyl)-4-methylthiazole-5-carboxamide | HCID 58992645 | — |
| Reactant | 3-Methoxycarbonylphenylboric acid | HCID 67170287 | — |
| Product | Methyl 3-[2-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]carbonylaminomethyl]morpholin-4-yl]benzoate | HCID 58992711 | 62% |
Reaction Steps
Using N-(morpholin-2-yl methyl)-2-(4-chlorophenyl)-4-methylthiazole-5-carboxamide (120 mg, 0.341 mmol) and 3-(methoxycarbonyl)phenylboric acid (123 mg, 0.682 mmol), the same procedure was followed as in Example 2 to give 102 mg (62%) of the desired compound as a colorless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902367B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-aedcc9a4aedd4e019cd54fed11063ed3 |
| Source note | uspto-grants-2011_03 |