HCID 67062970, compound → HCID 67063057, compound

Participants

Reaction Steps

Compound 25 (608 mg, 1.17 mmol) gave 364 mg substantially pure product (65%). [α]D=−11.8° (c=1, CHCl3); 1H NMR (CDCl3) 7.44-7.14 (m, 15H), 4.74 (d, 1H, J=11.6 Hz), 4.66-4.56 (m, 4H), 4.50 (d, 1H, J=9.4 Hz), 4.45 (d, 1H, J=11.4 Hz), 3.83 (d, 1H, J=10.7 Hz), 3.69 (dd, 1H, J=4.4, 10.7 Hz), 3.49 (m, 2H), 3.35 (m, 1H), 2.79 (m, 2H), 2.69 (m, H), 1.54 (m, 1H), 1.35 (t, 3H, J=7.3 Hz); 13C NMR (CDCl3): 138.8, 138.4, 135.8, 128.9, 128.7, 128.4, 128.2, 128.1, 127.4, 86.9, 81.3, 75.6, 73.8, 73.3, 72.5, 71.6, 69.8, 45.3, 36.7, 25.1, 20.3, 15.5; MS: calcd for C29H34O4SNa 501.2. found m/z 501.0 (M+Na).

Provenance & Evidence