3-Nitroquinolin-4-amine → HCID 178419901, compound

Participants

Reaction Steps

In steps (2) and (3) of Reaction Scheme V, a 3-nitroquinolin-4-amine or 3-nitro[1,5]naphthyridin-4-amine of Formula XLIII is first reduced to a quinoline-3,4-diamine or [1,5]naphthyridine-3,4-diamine of Formula XLIV, which is then treated with a carboxylic acid equivalent to provide a 1H-imidazo[4,5-c]quinoline or 1H-imidazo[4,5-c][1,5]naphthyridine of Formula XLV. Steps (2) and (3) of Reaction Scheme V can be carried out according to the methods described in steps (2) and (3) of Reaction Scheme I.

Provenance & Evidence