HCID 178419901, compound → HCID 178507385, compound

HRID 602258Notes

Reaction equation

HRID 602258 reaction equation
[NH:1]1[C:13]2[C:12]3[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=3[N:6]=[CH:5][C:4]=2[N:3]=[CH:2]1.[NH:14]1[C:26]2[C:25]3[N:24]=[CH:23][CH:22]=[CH:21][C:20]=3[N:19]=[CH:18][C:17]=2[N:16]=[CH:15]1>>[NH:1]1[C:13]2[C:12]3[C:7](=[C:8]([NH2:14])[CH:9]=[CH:10][CH:11]=3)[N:6]=[CH:5][C:4]=2[N:3]=[CH:2]1.[NH:14]1[C:26]2[C:25]3[C:20](=[C:21]([NH2:1])[CH:22]=[CH:23][N:24]=3)[N:19]=[CH:18][C:17]=2[N:16]=[CH:15]1

Participants

4

Reactant 2

HCID 178419901HCID 178419901, compoundHCID 1784207351h-Imidazo[4,5-c][1,5]naphthyridine

Product 2

HCID 178507385HCID 178507385, compoundHCID 178507867HCID 178507867, compound

Procedure

In steps (6) and (7) of Reaction Scheme IX, a 1H-imidazo[4,5-c]quinoline or 1H-imidazo[4,5-c][1,5]naphthyridine of Formula LXXIII is oxidized and then aminated to provide a 1H-imidazo[4,5-c]quinolin-6-amine or 1H-imidazo[4,5-c][1,5]naphthyridin-6-amine of Formula LXXV, a subgenus of Formulas I, II, III, and IV. Steps (6) and (7) of Reaction Scheme IX can be carried out as described in steps (5) and (6) of Reaction Scheme I.

Sources & evidence

ORD record
ord-f4c84d3e7df84f6eb88faee7e64d8644
Source dataset
uspto-grants-2011_03
Patent number
US07906506B2

Reaction notes

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