HCID 67273336, compound → HCID 67274034, compound

Participants

Reaction Steps

A pressure bottle was charged with platinum on carbon (5%, 0.27 g) followed by (2S)-2-[(3-nitroquinolin-4-yl)amino]propan-1-ol (1.11 g, 4.49 mmol) dissolved in 200 mL of toluene. The reaction mixture was shaken under H2 at 48 PSI (3.3×105 Pa). The next day the reaction was filtered through a pad of CELITE filter agent and rinsed with toluene. The solvent was removed under reduced pressure to give (2S)-2-[(3-aminoquinolin-4-yl)amino]propan-1-ol (1.13 g) as an orange oil.

Provenance & Evidence