5-Bromovaleryl chloride → HCID 11301286, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[C:7](=[O:22])[N:8]3[CH2:21][CH2:20][CH2:19][CH:9]3[N:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:11]=2[CH:12]=1.Br[CH2:24]CCCC(Cl)=O>>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([C:7](=[O:22])[N:8]3[CH2:21][CH2:20][CH2:19][CH2:24][CH:9]3[N:10]2[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)=[CH:5][CH:4]=1Participants
3
Procedure
Following the procedure for 6-methoxy-4-phenyl-2,3,3a,4-tetrahydropyrrolo[2,1-b]quinazolin-9(1H)-one, using 5-bromovaleroyl chloride in place of 4-bromobutyryl chloride, the titled compound was obtained.
Sources & evidence
- ORD record
- ord-d01b497f105a4d77bd73eaafe5344a91
- Source dataset
- uspto-grants-2011_03
- Patent number
- US07906521B2
Reaction notes
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