Trimethylsilyl isocyanate → HCID 43216490, compound

HRID 602428Notes

Reaction equation

HRID 602428 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]([NH2:8])[CH2:4][CH2:3]1.C[Si]([N:13]=[C:14]=[O:15])(C)C>>[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]([NH:8][C:14]([NH2:13])=[O:15])[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 70696Trimethylsilyl isocyanateHCID 27375314-Amino-1-methylpiperidine

Product 1

HCID 43216490HCID 43216490, compound

Procedure

(1-methyl-piperidin-4-yl)-urea was prepared from 1-methyl-piperidin-4-ylamine and trimethylsilylisocyanate, in analogy to Example 5.0; 1H-NMR (300 MHz, d6-DMSO) 5.86 (1H, d), 5.32 (2H, s), 3.21-3.38 (1H, m), 2.58-2.67 (2H, m), 2.11 (3H, s), 1.88-1.98 (2H, m), 1.65-1.72 (2H, m), 1.22-1.35 (2H, m).

Sources & evidence

ORD record
ord-fe24fbfa6e114a7eb394401f7e9ab869
Source dataset
uspto-grants-2011_03
Patent number
US07906533B2

Reaction notes

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