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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 602494Generated: October 31, 2026

Isopropyl iodide → tert-Butyl (2S,4S)-4-{[(5-fluoro-1-isopropyl-1H-indazol-3-yl)carbonyl]amino}-2-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/602494

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropyl iodideHCID 6362—
ReactantHCID 67270785HCID 67270785—
Producttert-Butyl (2S,4S)-4-{[(5-fluoro-1-isopropyl-1H-indazol-3-yl)carbonyl]amino}-2-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylateHCID 67271330—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 4 from tert-butyl (2S,4S)-4-{[(5-fluoro-1H-indazol-3-yl)carbonyl]amino}-2-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylate (step 1 of Example 25) and 2-iodopropane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07906532B2
Source datasetuspto-grants-2011_03
ORD IDord-de97a999d0ef4b68b911f6a5dad7f7d9
Source noteuspto-grants-2011_03