HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 11488848, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 3-[Bromo(4-chlorophenyl)methyl]benzonitrile | HCID 67055351 | — |
| Reactant | HCID 67065901 | HCID 67065901 | — |
| Product | HCID 11488848 | HCID 11488848 | — |
Reaction Steps
A sample of 0.233 mg (0.86 mmole) of 3-{(1S)-2-fluoro-1-[3-fluoro-5-(methylthio)phenyl]-2-methylpropyl}azetidine was alkylated with 263 mg (0.86 mmole) of 3-[bromo(4-chlorophenyl)methyl]benzonitrile and 0.975 mg (3 mmole) of Cs2CO3 as described in Step 2 of Example 79 to afford the title compound; Mass Spectrum: m/e=497 (M+1, 35Cl); 499 (M+1, 37Cl)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07906503B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-9cd174727bdc4b8091929efa61ce25d2 |
| Source note | uspto-grants-2011_03 |