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Hydrazine hydrate (1:1) → Benzenesulfonyl-acetic acid hydrazide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | Methyl phenylsulfonyl acetate | HCID 555619 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Benzenesulfonyl-acetic acid hydrazide | HCID 11378890 | 99.4% |
反応手順
To a stirred solution of 5.0 g (0.023 mol) of benzenesulfonyl-acetic acid methyl ester in 10 mL of MeOH at RT, 3.50 g (0.070 mol, 3 eq) of hydrazine hydrate were added. After one hour, the solvent and the excess of hydrazine were removed under reduced pressure, yielding 4.90 g (quantitative) of benzenesulfonyl-acetic acid hydrazide as a colorless oil, MS: 232 (MNH4+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07906546B2 |
| 出典データセット | uspto-grants-2011_03 |
| ORD ID | ord-1db2cf388b6442e6be5c771eb371d57b |
| 出典メモ | uspto-grants-2011_03 |