HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[Bromo(4-cyanophenyl)methyl]benzonitrile → Ethyl 3-(1-{1-[(4-cyanophenyl)(3-cyanophenyl)methyl]azetidin-3-yl}-2-fluoro-2-methylpropyl)-5-fluorobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[Bromo(4-cyanophenyl)methyl]benzonitrile | HCID 67055335 | — |
| Reactant | Ethyl 3-(1-azetidin-3-yl-2-fluoro-2-methylpropyl)-5-fluorobenzoate | HCID 67055353 | — |
| Product | Ethyl 3-(1-{1-[(4-cyanophenyl)(3-cyanophenyl)methyl]azetidin-3-yl}-2-fluoro-2-methylpropyl)-5-fluorobenzoate | HCID 67055347 | — |
Reaction Steps
Prepared from ethyl 3-(1-azetidin-3-yl-2-fluoro-2-methylpropyl)-5-fluorobenzoate and 3-[bromo(4-cyanophenyl)methyl]benzonitrile as described in Preparation 17, Part 5; Mass Spectrum: m/e=514.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07906652B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-acf08cc00cc94cf5aeef399f57ba6ae8 |
| Source note | uspto-grants-2011_03 |