反应详情

To 1-benzyl 4-tert-butyl 2-(hydroxymethyl)piperazine-1,4-dicarboxylate (0.4 g) in CH2Cl2 (10 ml) under argon was added Dess Martin periodinane (533 mg), the mixture stirred at room temperature for 16 hours, evaporated to half volume, saturated aqueous sodium bicarbonate and ethyl acetate added, the organic phase dried (MgSO4), and evaporated to give the title compound (228 mg, 57%).

1. customevaporated to half volume, saturated aqueous sodium bicarbonate and ethyl acetate
2. additionadded
3. dry with materialthe organic phase dried (MgSO4)
4. customevaporated