HCID 67158148, compound → HCID 57656854, compound

HRID 603246Notes

Reaction equation

HRID 603246 reaction equation
[CH:1]1([N:4]2[CH2:9][CH2:8][N:7](C(OCC3C=CC=CC=3)=O)[CH:6]([C:20]([N:22]3[CH2:27][CH2:26][N:25]([C:28]([NH:30][C:31]4[CH:36]=[CH:35][C:34]([Cl:37])=[C:33]([Cl:38])[CH:32]=4)=[O:29])[CH2:24][CH2:23]3)=[O:21])[CH2:5]2)[CH2:3][CH2:2]1.C1(N2CCC[C@H](CN3CCN(C(OCC4C=CC=CC=4)=O)CC3)C2)CC1>>[CH:1]1([N:4]2[CH2:9][CH2:8][NH:7][C@@H:6]([C:20]([N:22]3[CH2:23][CH2:24][N:25]([C:28]([NH:30][C:31]4[CH:36]=[CH:35][C:34]([Cl:37])=[C:33]([Cl:38])[CH:32]=4)=[O:29])[CH2:26][CH2:27]3)=[O:21])[CH2:5]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 67158148HCID 67158148, compoundHCID 67220711HCID 67220711, compound

Product 1

HCID 57656854HCID 57656854, compound

Procedure

The benzyl 4-cyclopropyl-2-[(4-{[(3,4-dichlorophenyl)amino]carbonyl}piperazin-1-yl)carbonyl]piperazine-1-carboxylate used in the above was prepared in a manner analogous to benzyl 4-{[(3R)-1-cyclopropylpiperidin-3-yl]methyl}piperazine-1-carboxylate.

Sources & evidence

ORD record
ord-1eb0f2f15c6e4d049ea8f4ea733a6dcb
Source dataset
uspto-grants-2011_03
Patent number
US07906645B2

Reaction notes

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