Diethyl Ether → HCID 135908415, compound

HRID 603263Notes

Reaction equation

HRID 603263 reaction equation
CCOCC.[C:6]([C:9]1[C:10]([O:29]C)=[CH:11][C:12]([O:27]C)=[C:13]([C:15]2[N:19]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[CH3:26])[N:18]=[CH:17][CH:16]=2)[CH:14]=1)([OH:8])=[O:7].B(Br)(Br)Br>ClCCl>[C:6]([C:9]1[C:10]([OH:29])=[CH:11][C:12]([OH:27])=[C:13]([C:15]2[N:19]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[CH3:26])[N:18]=[CH:17][CH:16]=2)[CH:14]=1)([OH:8])=[O:7]

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 25134Boron tribromideHCID 44249251HCID 44249251, compound

Product 1

HCID 135908415HCID 135908415, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1.6 Ether hydrolysis of “1d” using boron tribromide in dichloromethane under standard conditions gives the compound 5-(5-carboxy-2,4-dihydroxyphenyl)-1-(2-methylphenyl)-1H-pyrazole (“1e”).

Sources & evidence

ORD record
ord-11b7ed92386e4f8bb07fd1fadf7580b0
Source dataset
uspto-grants-2011_03
Patent number
US07906657B2

Reaction notes

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