Acetic Anhydride → HCID 9950375, compound

HRID 603272Notes

Reaction equation

HRID 603272 reaction equation
OC1C=C(C=CC=1)C1C(=O)C2C(=C(C)C(O)=CC=2)OC=1.[C:21]([O:24][C:25](=[O:27])[CH3:26])(=O)[CH3:22].C(OC1C=[CH:52][C:35]([C:36]2[C:45](=[O:46])[C:44]3[C:39](=[C:40]([CH3:51])[C:41]([O:47][C:48](=[O:50])[CH3:49])=[CH:42][CH:43]=3)[O:38][CH:37]=2)=[CH:34][CH:33]=1)(=O)C>N1C=CC=CC=1>[C:25]([O:24][C:21]1[CH:52]=[C:35]([CH:34]=[CH:33][CH:22]=1)[C:36]1[C:45](=[O:46])[C:44]2[C:39](=[C:40]([CH3:51])[C:41]([O:47][C:48](=[O:50])[CH3:49])=[CH:42][CH:43]=2)[O:38][CH:37]=1)(=[O:27])[CH3:26]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 9819870HCID 9819870, compoundHCID 672680083',7-Dihydroxy-8-methylisoflavone

Product 1

HCID 9950375HCID 9950375, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

3′,7-Diacetoxy-8-methylisoflavone was prepared from 3′,7-dihydroxy-8-methylisoflavone (1.3 g, 4.8 mmol), acetic anhydride (8 ml) and pyridine (1.5 ml) as described for 4′,7-diacetoxy-8-methylisoflavone. Yield: (1.2 g, 70%) m.p. 112° C. 1H NMR (CDCl3): δ 2.31 (s, 3H, CH3), 2.32, 2.39 (each s, 3H, OCOCH3), 7.13 (m, 2H, ArH), 7.37-7.45 (m, 3H, ArH), 8.1 (s, 1H, H2), 8.18 (d, 1H, J 8.7 Hz, H5). Mass spectrum: m/z 352 (M, 6%); 310 (35); 268 (100); 267 (60).

Sources & evidence

ORD record
ord-233fc2e3861044a5a1e82476bd72fc0a
Source dataset
uspto-grants-2011_03
Patent number
US07906660B2

Reaction notes

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