Acetic Anhydride → HCID 9907985, compound

HRID 603274Notes

Reaction equation

HRID 603274 reaction equation
[OH:1][C:2]1C=CC(C2C(=O)C3C(=C(C)C(O)=CC=3)OC=2)=CC=1OC.C(OC(=O)C)(=O)C.[C:30]([O:33][C:34]1[CH:55]=[CH:54][C:37]([C:38]2[C:47](=[O:48])[C:46]3[C:41](=[C:42]([CH3:53])[C:43]([O:49][C:50](=[O:52])[CH3:51])=[CH:44][CH:45]=3)[O:40][CH:39]=2)=[CH:36][CH:35]=1)(=[O:32])[CH3:31]>N1C=CC=CC=1>[C:30]([O:33][C:34]1[CH:55]=[CH:54][C:37]([C:38]2[C:47](=[O:48])[C:46]3[C:41](=[C:42]([CH3:53])[C:43]([O:49][C:50](=[O:52])[CH3:51])=[CH:44][CH:45]=3)[O:40][CH:39]=2)=[CH:36][C:35]=1[O:1][CH3:2])(=[O:32])[CH3:31]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 9819870HCID 9819870, compoundHCID 67266906HCID 67266906, compound

Product 1

HCID 9907985HCID 9907985, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

4′,7-Diacetoxy-3′-methoxy-8-methylisoflavone was prepared from 4′,7-dihydroxy-3′-methoxy-8-methylisoflavone (0.42 g, 1.4 mmol), acetic anhydride (2.6 ml) and pyridine (0.5 ml) as described for 4′,7-diacetoxy-8-methylisoflavone. Yield: (0.4 g, 74%) m.p. 209° C. 1H NMR (CDCl3): δ 2.22 (s, 3H, CH3), 2.32, 2.39 (each s, 3H, OCOCH3), 3.89 (s, 3H, OMe), 7.07-7.11 (m, 2H, ArH), 7.13 (d, 1H, J 8.6 Hz, H6), 7.32 (d, 1H, J 1.5 Hz, ArH), 8.09 (s, 1H, H2), 8.18 (d, 1H, J 8.7 Hz, H5).

Sources & evidence

ORD record
ord-a80cc47c93cd4dc2b12be7ed11b886f5
Source dataset
uspto-grants-2011_03
Patent number
US07906660B2

Reaction notes

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