Imidazole → HCID 9813510, compound

HRID 603281Notes

Reaction equation

HRID 603281 reaction equation
C([O:4][C:5]1[CH:6]=[C:7]([CH:22]=[CH:23][CH:24]=1)[C:8]1[CH2:9][O:10][C:11]2[C:16]([CH:17]=1)=[CH:15][CH:14]=[C:13]([O:18]C(=O)C)[CH:12]=2)(=O)C.N1C=CN=C1.O1C2C(=CC=C(O)C=2)C=C(C2C=CC(O)=CC=2)C1>C(O)C>[O:10]1[C:11]2[C:16](=[CH:15][CH:14]=[C:13]([OH:18])[CH:12]=2)[CH:17]=[C:8]([C:7]2[CH:22]=[CH:23][CH:24]=[C:5]([OH:4])[CH:6]=2)[CH2:9]1

Participants

5

Reactant 3

HCID 795ImidazoleHCID 219100PhenoxodiolHCID 67267311HCID 67267311, compound

Product 1

HCID 9813510HCID 9813510, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Isoflav-3-ene-3′,7-diol was prepared from 3′,7-diacetoxyisoflav-3-ene (0.09 g, 0.3 mmol) and imidazole (0.3 g) in ethanol (2.0 ml) as described for isoflav-3-ene-4′,7-diol. Yield: (0.04 g, 60%). 1H NMR (CDCl3+d6-DMSO): δ 4.94 (s, 2H, H2), 6.21 (d, 1H, J 2.0 Hz, H8), 6.29 (dd, 1H, J 2.3 Hz, 8.3 Hz, H6), 6.62 (m, 1H, ArH), 6.64 (bs, 1H, H4), 6.75-6.82 (m, 3H, ArH), 7.07 (t, 1H, J 7.9 Hz, ArH), 8.99-9.17 (bs, 2H, OH).

Sources & evidence

ORD record
ord-2a7699a043d14b8aae3a694e4283f28b
Source dataset
uspto-grants-2011_03
Patent number
US07906660B2

Reaction notes

Loading…