HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,6-Trifluorophenol → N-(2',3',6'-trifluorophenyl)-N-chloroacetyl-4-ethylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,6-Trifluorophenol | HCID 517988 | — |
| Reactant | 2-chloro-N-(4-ethylphenyl)acetamide | HCID 720962 | — |
| Product | N-(2',3',6'-trifluorophenyl)-N-chloroacetyl-4-ethylaniline | HCID 66897441 | — |
Reaction Steps
Same procedure as example 6a, starting from 2,3,6-trifluorophenol and 2-chloro-N-(4-ethylphenyl)acetamide. The crude intermediate N-(2′,3′,6′-trifluorophenyl)-4-ethylaniline was roughly purified by filtration on silica using toluene as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07906677B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-adc3893cfe5b46e49d1f920ea14d36df |
| Source note | uspto-grants-2011_03 |