2-chloro-N-(4-ethylphenyl)acetamide → N-(2'-chloro-6'-fluorophenyl)-N-chloroacetyl-4-ethylaniline

HRID 603351Notes

Reaction equation

HRID 603351 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1O.[Cl:10][CH2:11][C:12]([NH:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH3:22])=[CH:17][CH:16]=1)=[O:13]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[N:14]([C:12](=[O:13])[CH2:11][Cl:10])[C:15]1[CH:16]=[CH:17][C:18]([CH2:21][CH3:22])=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 7209622-chloro-N-(4-ethylphenyl)acetamideHCID 27737102-Chloro-6-fluorophenol

Product 1

HCID 66883619N-(2'-chloro-6'-fluorophenyl)-N-chloroacetyl-4-ethylaniline

Procedure

Same procedure as example 6a starting from 2-chloro-6-fluorophenol and 2-chloro-N-(4-ethylphenyl)acetamide.

Sources & evidence

ORD record
ord-b8f041f2a1494c33b580ea20431381e8
Source dataset
uspto-grants-2011_03
Patent number
US07906677B2

Reaction notes

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