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HRID6036

反应详情

EQUATION

反应方程式

HRID 6036 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)c1ccc(O)cc1
HCID7469

4-Hydroxyacetophenone

C8H8O2

结构：CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@@H](Br)SC[C@H]1OC(C)=O
HCID10926314

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](OC(C)=O)CS[C@H]1Oc1ccc(C(C)=O)cc1
HCID15067850

未命名化合物

收率 18%

AUXILIARIES

试剂、催化剂与溶剂

3
结构：[Cl-].[Cl-].[Zn+2]
催化剂HCID3007855

Zinc chloride

Cl2Zn

结构：[Ag+].c1c[n-]cn1
催化剂HCID10931941

未命名化合物

结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

If the procedure described in Preparation LXXXIII is followed starting from 2 g (14.7.10-3 mol) of 1-(4-hydroxyphenyl)ethanone, 2.8 g (16.10-3 mol) of silver imidazolate, 5.74 g (16.1.10-3 mol) of 2,3,4-tri-O-acetyl-5-thio-α-D-xylopyranosyl bromide and 4 g (29.3.10-3 mol) of zinc chloride in 100 ml of methylene chloride, 0.96 g (yield: 18%) of the expected product is obtained after purification by chromatography on silica gel using a toluene/ethyl acetate mixture (6/1 v/v) as the eluent.

WORKUP

后处理

  1. customIf the procedure described in Preparation LXXXIII