HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → Ethyl 2-acetyl-3-(dimethylamino)acrylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | Ethyl 2-acetyl-3-(dimethylamino)acrylate | HCID 3806790 | 99.3% |
Reaction Steps
Add ethyl acetoacetate (15 mL, 0.118 mol) to dimethoxymethyl-dimethyl-amine (19 mL, 0.142 mol) and reflux the mixture for 1 hr. Evaporate the mixture to give 2-dimethylaminomethylene-3-oxo-butyric acid ethyl ester (21.7 g, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07910588B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-2dc63bbebc7e408fb93b63af1b12f01c |
| Source note | uspto-grants-2011_03 |