HCID 2735754, compound → 3-{4-[4-(5-Chloro-2-methoxyphenyl)-piperazine-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one Monohydrochloride

HRID 604323Notes

Reaction equation

HRID 604323 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1(CC)[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][C:7]1=[O:15].[Cl:18][C:19]1[CH:20]=[CH:21][C:22]([O:31][CH3:32])=[C:23]([N:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)[CH:24]=1>>[ClH:1].[Cl:18][C:19]1[CH:20]=[CH:21][C:22]([O:31][CH3:32])=[C:23]([N:25]2[CH2:26][CH2:27][N:28]([CH2:2][CH2:3][CH2:4][CH2:5][CH:6]3[C:14]4[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=4)[NH:8][C:7]3=[O:15])[CH2:29][CH2:30]2)[CH:24]=1

Participants

3

Reactant 2

HCID 2735754HCID 2735754, compoundHCID 670406333-(4-Chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 670412063-{4-[4-(5-Chloro-2-methoxyphenyl)-piperazine-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one Monohydrochloride

Procedure

The title compound is prepared according to process B by applying processing method 2 starting from 3-(4-chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-one and 1-(5-chloro-2-methoxyphenyl)-piperazine.

Sources & evidence

ORD record
ord-1d19d2040d304d48995e19c7659e363e
Source dataset
uspto-grants-2011_03
Patent number
US07910591B2

Reaction notes

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