HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzothiazole → 2-Benzothiazolyl 3-piperidinopropyl ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzothiazole | HCID 11987 | — |
| Reactant | Sodium 3-piperidinopropanolate | HCID 23694275 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Benzothiazolyl 3-piperidinopropyl ether | HCID 9795591 | — |
Reaction Steps
Sodium 3-piperidinopropanolate (5 mmol) and 5 mmol of 2-chlorobenzothiazole in 20 ml of dry tetrahydrofurane were refluxed for 12 hours. The suspension was filtered and the solvent evaporated under reduced pressure. The product was crystallized with oxalic acid from diethyl ether/ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07910605B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-aa97bd1dfcb1454d9bb914ada6e17f53 |
| Source note | uspto-grants-2011_03 |