Methyl iodide → 5-(2-Methyl-2H-tetrazol-5-yl)-4-thiophen-2-yl-thiazol-2-ylamine

HRID 604471Notes

Reaction equation

HRID 604471 reaction equation
[NH:1]1[C:5]([CH2:6][C:7]([C:9]2[S:10][CH:11]=[CH:12][CH:13]=2)=O)=[N:4][N:3]=[N:2]1.[CH3:14]I.[NH2:16][C:17]([NH2:19])=[S:18]>>[CH3:14][N:2]1[N:3]=[N:4][C:5]([C:6]2[S:18][C:17]([NH2:19])=[N:16][C:7]=2[C:9]2[S:10][CH:11]=[CH:12][CH:13]=2)=[N:1]1

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 2723790ThioureaHCID 178520396HCID 178520396, compound

Product 1

HCID 866307035-(2-Methyl-2H-tetrazol-5-yl)-4-thiophen-2-yl-thiazol-2-ylamine

Procedure

Prepared from 2-(1H-tetrazol-5-yl)-1-thiophen-2-yl-ethanone and MeI and thiourea.

Sources & evidence

ORD record
ord-9a9ed19309e84e18afa0aa0d217743e6
Source dataset
uspto-grants-2011_03
Patent number
US07910613B2

Reaction notes

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