HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → HCID 11597583, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | (3,4-Dimethoxyphenyl)acetic acid | HCID 7139 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 57709598 | HCID 57709598 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 11597583 | HCID 11597583 | 13% |
Reaction Steps
200 μL of a 0.6M stock solution of (3,4-dimethoxy-phenyl)-acetic acid was mixed with 200 μL of a 0.3M stock solution of EDC containing 1 eq. of ethyl-diisopropyl-amine. Then 100 μL of a 0.3M stock solution of 5-(2-ethyl-2H-tetrazol-5-yl)-4-phenyl-thiazol-2-ylamine containing 1 eq. of DMAP was added. The reaction mixture was shaken overnight at ambient temperature. Purification was performed by preparative LC-MS. Yield: 13%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07910613B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-1cd760de9f684b029e9fa6150c3aad5b |
| Source note | uspto-grants-2011_03 |