2-Thiopheneacetyl chloride → N-[5-(3-Methyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-thiazol-2-yl]-2-thiophen-2-yl-acetamide

HRID 604520Notes

Reaction equation

HRID 604520 reaction equation
[CH3:1][C:2]1[N:6]=[C:5]([C:7]2[S:11][C:10]([NH2:12])=[N:9][C:8]=2[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[O:4][N:3]=1.[S:19]1[CH:23]=[CH:22][CH:21]=[C:20]1[CH2:24][C:25](Cl)=[O:26]>>[CH3:1][C:2]1[N:6]=[C:5]([C:7]2[S:11][C:10]([NH:12][C:25](=[O:26])[CH2:24][C:20]3[S:19][CH:23]=[CH:22][CH:21]=3)=[N:9][C:8]=2[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[O:4][N:3]=1

Participants

3

Reactant 2

HCID 1623622-Thiopheneacetyl chlorideHCID 577095965-(3-Methyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-thiazol-2-ylamine

Product 1

HCID 11589039N-[5-(3-Methyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-thiazol-2-yl]-2-thiophen-2-yl-acetamide

Procedure

Prepared from 5-(3-methyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-thiazol-2-ylamine and thiophen-2-yl-acetyl chloride.

Sources & evidence

ORD record
ord-0f9e4472cfde4467bfcd9829c4d1c35c
Source dataset
uspto-grants-2011_03
Patent number
US07910613B2

Reaction notes

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