(3,4-Dimethoxyphenyl)acetyl chloride → 2-(3,4-Dimethoxy-phenyl)-N-[5-(2-methyl-2H-tetrazol-yl)-4-thiophen-2-yl-thiazol-2-yl]-acetamide

HRID 604530Notes

Reaction equation

HRID 604530 reaction equation
[CH3:1][N:2]1[N:6]=[N:5][C:4]([C:7]2[S:11][C:10]([NH2:12])=[N:9][C:8]=2[C:13]2[S:14][CH:15]=[CH:16][CH:17]=2)=[N:3]1.[CH3:18][O:19][C:20]1[CH:21]=[C:22]([CH2:28][C:29](Cl)=[O:30])[CH:23]=[CH:24][C:25]=1[O:26][CH3:27]>>[CH3:18][O:19][C:20]1[CH:21]=[C:22]([CH2:28][C:29]([NH:12][C:10]2[S:11][C:7]([C:4]3[N:5]=[N:6][N:2]([CH3:1])[N:3]=3)=[C:8]([C:13]3[S:14][CH:15]=[CH:16][CH:17]=3)[N:9]=2)=[O:30])[CH:23]=[CH:24][C:25]=1[O:26][CH3:27]

Participants

3

Reactant 2

HCID 3604458(3,4-Dimethoxyphenyl)acetyl chlorideHCID 866307035-(2-Methyl-2H-tetrazol-5-yl)-4-thiophen-2-yl-thiazol-2-ylamine

Product 1

HCID 117191762-(3,4-Dimethoxy-phenyl)-N-[5-(2-methyl-2H-tetrazol-yl)-4-thiophen-2-yl-thiazol-2-yl]-acetamide

Procedure

Prepared from 5-(2-methyl-2H-tetrazol-5-yl)-4-thiophen-2-yl-thiazol-2-ylamine and (3,4-dimethoxy-phenyl)-acetyl chloride.

Sources & evidence

ORD record
ord-17e89809dbc0412cb76c9818725d4fc6
Source dataset
uspto-grants-2011_03
Patent number
US07910613B2

Reaction notes

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