(2S)-2-t-butoxycarbonylamino-2-ethyl-3-n-hexanoyloxy-1-propanal → (2R)-2-t-Butoxycarbonylamino-2-ethyl-1-n-hexanoyloxy-4-(1-methylpyrrol-2-yl)-3-butene

Participants

Reaction Steps

The reaction was carried out in the similar manner to Reference example 1 (1d) using (1-methylpyrrol-2-yl)methyltriphenylphosphonium iodide obtained in Reference example 1 (1c) and (2S)-2-t-butoxycarbonylamino-3-n-hexanoyloxy-2-ethyl-1-propanal obtained in Reference example 2 (2b) as starting materials to obtain the title compound (yield: 69%).

Provenance & Evidence