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HRID6046

反应详情

EQUATION

反应方程式

HRID 6046 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])c1ccccc1O
HCID6947

2-Nitrophenol

C6H5NO3

结构：CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@@H](Br)SC[C@H]1OC(C)=O
HCID10926314

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](OC(C)=O)CS[C@H]1Oc1ccccc1[N+](=O)[O-]
HCID15067858

未命名化合物

收率 15.3%

AUXILIARIES

试剂、催化剂与溶剂

3
结构：[Cl-].[Cl-].[Zn+2]
催化剂HCID3007855

Zinc chloride

Cl2Zn

结构：[Ag+].c1c[n-]cn1
催化剂HCID10931941

未命名化合物

结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

If the procedure described in Preparation LXXXIII is followed starting from 2 g (14.4.10-3 mol) of 2-nitrophenol, 2.5 g (14.2.10-3 mol) of silver imidazolate, 6 g (15.7.10-3 mol) of 2,3,4-tri-O-acetyl-5-thio-α-D-xylopyranosyl bromide and 4 g (29.3.10-3 mol) of zinc chloride in 80 ml of methylene chloride, 0.91 g (yield: 15%) of the expected product is obtained after purification by chromatography on silica gel using a hexane/ethyl acetate mixture (2/1 v/v) as the eluent, and precipitation in ether.

WORKUP

后处理

  1. customIf the procedure described in Preparation LXXXIII