HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Pentafluorobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 2,3,4,5,6-Pentafluorobenzenesulfonyl chloride | HCID 70026 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Pentafluorobenzenesulfonamide | HCID 2063927 | 36% |
Reaction Steps
Under room temperature, a solution of 468 g of pentafluorobenzenesulfonyl chloride in acetone was added dropwise to an aqueous solution containing 964 g of ammonium chloride, during which a pH was adjusted to 7 with an aqueous sodium hydroxide solution. The precipitated product was filtered, and recrystallized from toluene to obtain 156 g of pentafluorobenzenesulfonamide as white crystals. A structure was confirmed by 1H-NMR, 19F-NMR and IR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07910686B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-9e29f437fa32492cbe862a61782d3444 |
| Source note | uspto-grants-2011_03 |