2-Mercaptobenzoic Acid → HCID 59658526, compound

Participants

Reaction Steps

To bromoacetophenone (394.09 mg, 1.62 mmole) and anhydrous K2CO3 (896 mg, 6.48 mmole) in ethanol (20 ml), 250 mg (1.62 mmole) 2-mercaptobenzoic acid was added and the mixture refluxed overnight. The solvent was evaporated and water added to the solid residue. The aqueous layer was acidified to yield a precipitate which was filtered and dried (487 mg). m/z 315 (M−1)+. 1HNMR (DMSO) δ 4.75 (s, 2H, —CH2-), 7.22 (1H, t, ArH), 7.47 (2H, t, 2×ArH), 7.87 (1H, d, ArH), 8.06 (2H, d, 2×ArH), 8.15 (2H, d, 2×ArH).

Provenance & Evidence