反应详情

30 mg of 10% palladium-on-charcoal are added to a solution of 150 mg (0.36.10-3 mol) of 4-nitrophenyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside in acetic anhydride, under a nitrogen atmosphere, and the reaction mixture obtained is then kept under hydrogen pressure (3.5.105Pa) at 50° C. for 15 hours. After filtration, the mixture is evaporated to dryness under reduced pressure and the residue obtained is purified by chromatography using a methylene chloride/methanol mixture (98/2 v/v) as the eluent to give 80 mg (yield: 51%) of the expected product.

1. customthe reaction mixture obtained
2. customat 50° C.
3. customfor 15 hours
4. filtrationAfter filtration
5. customthe mixture is evaporated to dryness under reduced pressure
6. customthe residue obtained
7. customis purified by chromatography